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Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

simvastatin

Pronunciation: SIM va sta tin

Brand: Flolipid, Zocor

Zocor

slide 1 of 57, Zocor,

80 mg, capsule, red, imprinted with 543, 80

Image of Zocor
slide 1 of 57
    

Zocor

slide 2 of 57, Zocor,

5 mg, shield, yellow, imprinted with ZOCOR, MSD 726

Image of Zocor
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Zocor

slide 3 of 57, Zocor,

10 mg, oval, orange, imprinted with MSD 735

Image of Zocor
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Zocor

slide 4 of 57, Zocor,

20 mg, oval, brown, imprinted with MSD 740

Image of Zocor
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Zocor

slide 5 of 57, Zocor,

40 mg, oval, red, imprinted with MSD 749

Image of Zocor
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Simvastatin

slide 6 of 57, Simvastatin,

5 mg, round, yellow, imprinted with TV, 7152

Image of Simvastatin
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Simvastatin

slide 7 of 57, Simvastatin,

10 mg, round, pink, imprinted with TV, 7153

Image of Simvastatin
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Simvastatin

slide 8 of 57, Simvastatin,

20 mg, round, tan, imprinted with TV, 7154

Image of Simvastatin
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Simvastatin

slide 9 of 57, Simvastatin,

40 mg, round, red, imprinted with TV, 7155

Image of Simvastatin
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Simvastatin

slide 10 of 57, Simvastatin,

80 mg, capsule, red, imprinted with TV, 7156

Image of Simvastatin
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Simvastatin

slide 11 of 57, Simvastatin,

10 mg, round, pink, imprinted with A, 01

Image of Simvastatin
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Simvastatin

slide 12 of 57, Simvastatin,

20 mg, round, pink, imprinted with A, 02

Image of Simvastatin
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Simvastatin

slide 13 of 57, Simvastatin,

40 mg, round, pink, imprinted with A, 03

Image of Simvastatin
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Simvastatin

slide 14 of 57, Simvastatin,

80 mg, oblong, pink, imprinted with A, 04

Image of Simvastatin
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Simvastatin

slide 15 of 57, Simvastatin,

10 mg, oval, red, imprinted with S4

Image of Simvastatin
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Simvastatin

slide 16 of 57, Simvastatin,

20 mg, oval, red, imprinted with S5

Image of Simvastatin
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Simvastatin

slide 17 of 57, Simvastatin,

40 mg, oval, red, imprinted with S6

Image of Simvastatin
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Simvastatin

slide 18 of 57, Simvastatin,

80 mg, capsule, red, imprinted with SMV, 80

Image of Simvastatin
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Simvastatin

slide 19 of 57, Simvastatin,

5 mg, round, red, imprinted with SI

Image of Simvastatin
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Simvastatin

slide 20 of 57, Simvastatin,

40 mg, oval, white, imprinted with logo 640

Image of Simvastatin
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Simvastatin

slide 21 of 57, Simvastatin,

80 mg, capsule, pink, imprinted with A, 04

Image of Simvastatin
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Simvastatin

slide 22 of 57, Simvastatin,

10 mg, round, pink, imprinted with TV, 7153

Image of Simvastatin
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Simvastatin

slide 23 of 57, Simvastatin,

20 mg, round, brown, imprinted with TV, 7154

Image of Simvastatin
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Simvastatin

slide 24 of 57, Simvastatin,

5 mg, round, yellow, imprinted with A, 15

Image of Simvastatin
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Simvastatin

slide 25 of 57, Simvastatin,

10 mg, round, pink, imprinted with A, 01

Image of Simvastatin
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Simvastatin

slide 26 of 57, Simvastatin,

20 mg, round, pink, imprinted with A, 02

Image of Simvastatin
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Simvastatin

slide 27 of 57, Simvastatin,

40 mg, round, pink, imprinted with A, 03

Image of Simvastatin
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Simvastatin

slide 28 of 57, Simvastatin,

80 mg, capsule, pink, imprinted with A, 04

Image of Simvastatin
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Simvastatin

slide 29 of 57, Simvastatin,

5 mg, round, brown, imprinted with RDY, 197

Image of Simvastatin
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Simvastatin

slide 30 of 57, Simvastatin,

10 mg, round, brown, imprinted with RDY, 198

Image of Simvastatin
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Simvastatin

slide 31 of 57, Simvastatin,

80 mg, oval, brown, imprinted with RDY, 268

Image of Simvastatin
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Simvastatin

slide 32 of 57, Simvastatin,

20 mg, round, tan, imprinted with RX791

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Simvastatin

slide 33 of 57, Simvastatin,

40 mg, round, red, imprinted with RX792

Image of Simvastatin
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Simvastatin

slide 34 of 57, Simvastatin,

80 mg, round, red, imprinted with RX793

Image of Simvastatin
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Simvastatin

slide 35 of 57, Simvastatin,

5 mg, round, yellow, imprinted with A, 15

Image of Simvastatin
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Simvastatin

slide 36 of 57, Simvastatin,

10 mg, round, pink, imprinted with A, 01

Image of Simvastatin
slide 36 of 57
    

Simvastatin

slide 37 of 57, Simvastatin,

20 mg, round, pink, imprinted with A, 02

Image of Simvastatin
slide 37 of 57
    

Simvastatin

slide 38 of 57, Simvastatin,

40 mg, round, pink, imprinted with A, 03

Image of Simvastatin
slide 38 of 57
    

Simvastatin

slide 39 of 57, Simvastatin,

80 mg, oblong, pink, imprinted with A, 04

Image of Simvastatin
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Simvastatin

slide 40 of 57, Simvastatin,

10 mg, oval, peach, imprinted with LL, C02

Image of Simvastatin
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Simvastatin

slide 41 of 57, Simvastatin,

20 mg, oval, tan, imprinted with LL, C03

Image of Simvastatin
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Simvastatin

slide 42 of 57, Simvastatin,

40 mg, oval, red, imprinted with LL, C04

Image of Simvastatin
slide 42 of 57
    

Simvastatin

slide 43 of 57, Simvastatin,

80 mg, oblong, red, imprinted with LL, C05

Image of Simvastatin
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Simvastatin

slide 44 of 57, Simvastatin,

5 mg, round, tan, imprinted with LL, C01

Image of Simvastatin
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Simvastatin

slide 45 of 57, Simvastatin,

5 mg, oval, white, imprinted with ZA19

Image of Simvastatin
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Simvastatin

slide 46 of 57, Simvastatin,

80 mg, capsule, white, imprinted with ZA23

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Simvastatin

slide 47 of 57, Simvastatin,

10 mg, round, pink, imprinted with SV 10, LOGO

Image of Simvastatin
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Simvastatin

slide 48 of 57, Simvastatin,

10 mg, round, pink, imprinted with 93, 7153

Image of Simvastatin
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Simvastatin

slide 49 of 57, Simvastatin,

20 mg, round, tan, imprinted with SV 20, LOGO

Image of Simvastatin
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Simvastatin

slide 50 of 57, Simvastatin,

40 mg, round, pink, imprinted with SV 40, LOGO

Image of Simvastatin
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Simvastatin

slide 51 of 57, Simvastatin,

5 mg, round, white, imprinted with LOGO, SV 5

Image of Simvastatin
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Simvastatin

slide 52 of 57, Simvastatin,

80 mg, oblong, pink, imprinted with SV 80, LOGO

Image of Simvastatin
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Zocor

slide 53 of 57, Zocor,

10 mg, oval, orange, imprinted with MSD 735

Image of Zocor
slide 53 of 57
    

Zocor

slide 54 of 57, Zocor,

20 mg, oval, brown, imprinted with MSD 740

Image of Zocor
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Zocor

slide 55 of 57, Zocor,

40 mg, shield, pink, imprinted with ZOCOR, MSD 749

Image of Zocor
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Zocor

slide 56 of 57, Zocor,

5 mg, shield, yellow, imprinted with ZOCOR, MSD 726

Image of Zocor
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Zocor

slide 57 of 57, Zocor,

80 mg, oblong, red, imprinted with 543, 80

Image of Zocor
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What is the most important information I should know about simvastatin?

You should not take simvastatin if you are pregnant or breast-feeding, or if you have active liver disease.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Stop taking simvastatin and tell your doctor right away if you become pregnant.

What is simvastatin?

Simvastatin is used to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides, and increase levels of "good" cholesterol (high-density lipoprotein, or HDL).

Simvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in people with diabetes, coronary heart disease, or other risk factors.

Simvastatin is used in adults and children who are at least 10 years old.

Simvastatin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking simvastatin?

You should not take simvastatin if you are allergic to it, or if:

  • you have active liver disease; or
  • you are pregnant or breast-feeding.

Some medicines can cause unwanted or dangerous effects when used with simvastatin. Your doctor may change your treatment plan if you also use medicine such as:

  • cyclosporine;
  • danazol;
  • gemfibrozil;
  • imatinib;
  • lomitapide;
  • nefazodone;
  • an antibiotic or antifungal medicine;
  • tuberculosis medicine;
  • heart or blood pressure medication; or
  • antiviral medicine to treat hepatitis C or HIV/AIDS.

Tell your doctor if you have ever had:

  • liver disease;
  • kidney disease;
  • diabetes;
  • a thyroid disorder;
  • if you are of Asian descent; or
  • if you drink more than 2 alcoholic beverages daily.

Simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Do not use simvastatin if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine. Stop taking simvastatin and tell your doctor right away if you become pregnant.

It is not safe to breast-feed a baby while you are using this medicine.

How should I take simvastatin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Simvastatin is usually taken in the evening or at bedtime.

Take simvastatin oral suspension (liquid) on an empty stomach.

Shake the liquid for at least 20 seconds before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

You may need to take simvastatin on a long-term basis. You may need to stop using simvastatin for a short time if you have surgery or a medical emergency. Do not stop taking this medicine unless your doctor tells you to.

Simvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.

You will need frequent medical tests.

Store at room temperature away from moisture, heat, and light.

Do not refrigerate or freeze the liquid medicine. Throw away any liquid that has not been used within 1 month after you first opened the bottle.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking simvastatin?

Grapefruit may interact with simvastatin and lead to unwanted side effects. Avoid the use of grapefruit products.

Avoid eating foods high in fat or cholesterol, or simvastatin will not be as effective.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

What are the possible side effects of simvastatin?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

In rare cases, simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Also call your doctor at once if you have:

  • liver problems --loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • headache;
  • nausea, stomach pain, constipation; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect simvastatin?

Tell your doctor about all your other medicines, especially:

  • any other cholesterol medication --niacin, fenofibrate, fenofibric acid, and others; or
  • a blood thinner --warfarin, Coumadin, Jantoven.

This list is not complete and many other drugs may affect simvastatin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about simvastatin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 17.01. Revision date: 10/15/2018.

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