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fremanezumab

Pronunciation: FREE ma NEZ ue mab

Brand: Ajovy

What is the most important information I should know about fremanezumab?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is fremanezumab?

Fremanezumab is used to prevent migraine headaches in adults.

Fremanezumab may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using fremanezumab?

You should not use fremanezumab if you are allergic to it.

Fremanezumab is not approved for use by anyone younger than 18 years old.

Tell your doctor if you are pregnant. It is not known whether this medicine will harm an unborn baby. However, having migraines during pregnancy may cause complications such as preeclampsia (which can lead to medical problems in both mother and baby). The benefit of preventing migraines may outweigh any risks to the baby.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I use fremanezumab?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Fremanezumab is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

Fremanezumab is usually given as 1 injection once a month, or as 3 injections (in separate syringes) once every 3 months.

Read and carefully follow any Instructions for Use provided with your medicine. Do not use fremanezumab if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.

Prepare your injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

Store fremanezumab in the original carton in a refrigerator, protected from light. Do not freeze or shake this medicine.

Take the medicine out of the refrigerator and let it reach room temperature for 30 minutes before injecting your dose. Do not warm the medicine with hot water, sunlight, or a microwave.

You may store fremanezumab for up to 24 hours at room temperature. Throw the medicine away if it has been at room temperature for 24 hours or longer.

Each single-use prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Use the medicine as soon as you remember, and then restart your regular injection schedule 1 month or 3 months later.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using fremanezumab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of fremanezumab?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

An allergic reaction to fremanezumab can occur up to 1 month after an injection.

Common side effects may include:

  • pain, redness, or a hard lump where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect fremanezumab?

Other drugs may affect fremanezumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about fremanezumab.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 1.01. Revision date: 10/3/2018.

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